Former factory blocks on Pernerova, new office buildings on Rohanské nábřeží and metro line B, just east of the centre.

Rohanské nábřeží 678/23,River Garden, 5th floor,8, 18600
Private office from €334/desk/month

Rohanské nábřeží 693/10, 186 00
Day Pass from €27/day · Desk from €205/mo

Pernerova 702/39, 186 00
Day Pass from €27/day · Meeting Room from €21/hr

Pernerova 727/40a, 186 00
Day Pass from €27/day · Desk from €205/mo

Pernerova 51, 186 00
Day Pass from €25/day · Meeting Room from €16/hr

Pernerova 697/35, 186 00
Day Pass from €27/day · Meeting Room from €21/hr

Karolinská 654/2,Praha 8, 18600
Private office from €356/desk/month

Thámova 137/16, 186 00
Karlín, east of the centre along the Vltava, was Prague's first suburb: building began in 1817, and it has been part of the city since 1922. The August 2002 flood hit Karlín harder than any other part of Prague. Afterwards much of it was converted into offices, by renovating old factory blocks or building new ones. Choose Karlín when you want a modern office building with metro line B at the door. The historic centre is the alternative when the address itself has to impress.
Karlín was laid out from 1817 and named after Caroline Augusta of Bavaria, wife of Emperor Francis I; its German name was Karolinenthal. It was Prague's first suburb and grew into an industrial one: ČKD, once one of the world's major tram producers, had works here. The Negrelli Viaduct, opened in 1850, still carries the railway across the district. Along Pernerova, blocks of the old industrial suburb survive, and former ČKD buildings such as Kotelna (the Boiler Room) now hold modern offices behind their factory fronts.
After the August 2002 flood, much of Karlín was rebuilt as offices, and new office buildings now line the river on Rohanské nábřeží. Scott.Weber Workspace runs three houses on Pernerova (Praga Studios, Praga Office & Garden and PernerKarlín) and a fourth, Rustonka, on Rohanské nábřeží. WorkLounge is in Forum Karlín, the Ricardo Bofill building on Pernerova; Spaces is in Nile House by Florenc; Regus is in River Garden on Rohanské nábřeží; and a landlord runs a shared office on Thámova. Karlín suits teams that want a modern building close to the centre.
After 2002, Karlín filled with offices. Large office buildings went up along Rohanské nábřeží, and in 2022 Prague's planning institute IPR said most development was happening around Rohanský ostrov by the river. Flexible space is growing across the city: according to Savills, Prague had 130,500 m² of flexible workspace in December 2025, 60 % more than in 2019.
Karlínské náměstí, in front of the Church of Saints Cyril and Methodius, has been revitalised and hosts street festivals and farmers' markets. Forum Karlín on Pernerova holds concerts, congresses and gala dinners in its multifunctional hall.
Metro: Line B (yellow) runs under Karlín with two stations, Křižíkova and Invalidovna. Florenc, at the western edge, is the interchange between lines B and C (red). From Florenc, line B reaches Náměstí Republiky and Můstek in the centre.
Tram: Trams run along Sokolovská between Florenc and Palmovka, with stops at Karlínské náměstí, Křižíkova and Invalidovna.
Walking: From Karlínské náměstí, Florenc is about 10 minutes on foot and náměstí Republiky about 20 minutes.
Airport: Trolleybus 59 runs from Václav Havel Airport to Nádraží Veleslavín on metro line A (green); change at Můstek to line B for Florenc and Křižíkova. The Airport Express (AE) bus runs to Praha hlavní nádraží, one stop on line C from Florenc.
Invalidovna A Baroque building by Kilian Ignaz Dientzenhofer, built in 1731–1737 as a home for war veterans. The metro station on line B is named after it.
Church of Saints Cyril and Methodius A neo-Romanesque basilica on Karlínské náměstí, built in 1854–1863 to plans by Carl Roesner and Vojtěch Ignác Ullmann.
Negrelli Viaduct The railway viaduct opened on 1 June 1850, is about 1.1 km long and is named after Alois Negrelli.
Forum Karlín Designed by Ricardo Bofill on the site of a 1908 boiler house; its multifunctional hall hosts concerts and congresses.
Choose Karlín if you want a modern office building near the centre: much of the district was rebuilt as offices after the 2002 flood, and metro line B stops at Křižíkova and Invalidovna. Staré Město and Nové Město are the alternative when you want a historic address.
Scott.Weber Workspace runs four houses: Praga Studios, Praga Office & Garden and PernerKarlín on Pernerova, and Rustonka on Rohanské nábřeží. WorkLounge is in Forum Karlín, Spaces in Nile House by Florenc, Regus in River Garden on Rohanské nábřeží, and a landlord runs a shared office on Thámova.
Křižíkova and Invalidovna, both on line B (yellow), are in the district. Florenc, at the western edge, connects lines B and C.
Take trolleybus 59 to Nádraží Veleslavín, then metro line A to Můstek and line B to Florenc or Křižíkova. Or take the Airport Express (AE) bus to Praha hlavní nádraží and ride metro line C one stop to Florenc.
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The August 2002 flood hit Karlín harder than any other part of Prague. Afterwards much of the district was converted into offices, by renovating old factory buildings or building new ones, many of them along the river on Rohanské nábřeží.
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